metaxalone

Metaxalone is a centrally acting skeletal muscle relaxant used as an adjunct to rest and physical therapy for the relief of discomfort associated with acute, painful musculoskeletal conditions. Although its exact molecular mechanism of action remains uncharacterized, its therapeutic effects are believed to stem from general central nervous system (CNS) depression. Unlike some other muscle relaxants, metaxalone is noted for a relatively low potential for sedation, though it can still cause side effects such as dizziness, drowsiness, and gastrointestinal upset. It was originally developed by A.H. Robins and received FDA approval in 1962. It is currently available both as the brand-name drug Skelaxin and in various generic formulations.

Brand names

SkelaxinMetaxall

Other names

metaxalone