Drug intelligence / Profile preview

metformin + myo-inositol + d-chiro-inositol

Development stage
Phase 1
Modality
Small Molecules
Administration
Oral
01

Overview

This is a fixed-dose combination of three agents—metformin, myo-inositol, and d-chiro-inositol—used primarily for the management of polycystic ovary syndrome (PCOS). All three components act as insulin sensitizers but through different mechanisms. Metformin is a biguanide that decreases hepatic glucose production and increases peripheral insulin sensitivity. Myo-inositol and d-chiro-inositol are stereoisomers involved in cellular signaling pathways related to insulin action; they help improve ovarian function, regulate menstrual cycles, promote ovulation, and reduce hyperandrogenism. The combination has been shown to improve clinical symptoms (such as menstrual irregularity), metabolic parameters (insulin resistance), hormonal profiles (testosterone levels), and quality of life in women with PCOS. Some studies suggest the combination may allow for lower individual drug dosages without loss of efficacy[1][4][5].

Other names
metformin + myoinositol + d-chiro-inositolmetformin + MI + DCI
02

Targets

AMPK (Adenosine monophosphate–activated protein kinase)ND1 (Mitochondrial electron transport chain complex I)

Beyond the preview

Go deeper on metformin + myo-inositol + d-chiro-inositol.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on metformin + myo-inositol + d-chiro-inositol.

Gosset Free

Get started with Gosset.

Enter your corporate email.

Work email preferred.

Book a call