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This is an investigational combination therapy comprising the biguanide antidiabetic agent metformin and an extract from the root of *Scutellaria baicalensis*, a traditional medicinal herb. Developed by researchers led by Dr. Namyi Gu at Dongguk University, the therapy is intended for the treatment of type 2 diabetes mellitus. The *S. baicalensis* extract contains bioactive flavonoids such as baicalin and wogonoside. Clinical studies suggest that the combination works synergistically to improve glucose tolerance and lipid profiles while reducing systemic inflammation. A key proposed mechanism involves the modulation of the gut microbiota, specifically increasing the abundance of beneficial bacteria like *Lactobacillus* and *Akkermansia*.
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