Metformin glycinate

Metformin glycinate is a derivative of metformin with a different pharmacokinetic profile compared to the commonly used metformin hydrochloride. It is developed as an antihyperglycemic agent for the management of type 2 diabetes mellitus. Like standard metformin, it acts primarily by decreasing hepatic glucose production (gluconeogenesis), reducing intestinal absorption of glucose, and increasing insulin sensitivity in peripheral tissues. Clinical studies suggest that metformin glycinate may have additional effects on inflammatory mediators and could offer improved safety and tolerability over traditional formulations. Its mechanism includes inhibition of mitochondrial complex I activity and modulation of pro-inflammatory cytokines[5][8].

Brand names

Glicenex

Other names

METFORMIN GLYCINATE121369-64-0Metformin glycinate [INN]UNII-YEI21W005YUNII-YEI-21W005YUNII-YEI 21W005YYEI21W005YYEI-21W005YYEI 21W005Y