Drug intelligence / Profile preview

methenamine + methylthioninium + acriflavine + atropa belladonna

Development stage
Unknown
Modality
Small Molecules
Administration
Oral
01

Overview

A urinary antiseptic combination used primarily for treating urinary tract infections (UTIs) and related symptoms. It contains four active ingredients that work together to provide antimicrobial and symptomatic relief effects. This combination contains methenamine (250mg), methylthioninium chloride (20mg), acriflavine (15mg), and Atropa belladonna L. extract (15mg). It's used in the treatment of recurrent cystitis and urinary tract infections. **Mechanism of Action:** * **Methenamine**: Decomposes in acidic urine to release formaldehyde, which has antimicrobial properties. * **Methylthioninium (Methylene blue)**: Acts as an oxidation-reduction agent with antiseptic properties. * **Acriflavine**: Provides additional antimicrobial activity. * **Atropa belladonna L.**: Contains anticholinergic compounds that help relieve urinary tract spasms and discomfort.

Brand names
Cystex
Other names
methenamine + methylthioninium + acriflavine + atropa belladona
02

Targets

NeuraminidasemAChR (Muscarinic acetylcholine receptors)MAOA (Monoamine oxidase A)

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