Drug intelligence / Profile preview

methylated spirit

Development stage
Phase 2
Modality
Implantable Devices → Device-based Delivery → Drug Delivery Systems, Small Molecules, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Inhalation Devices → Device-based Delivery → Drug Delivery Systems
Administration
Topical
01

Overview

Methylated spirit is a clear, colorless liquid consisting primarily of ethanol that has been rendered undrinkable by the addition of various chemical denaturants. The most common additive is methanol (typically at least 10%), but other substances such as pyridine, isopropyl alcohol, acetone, methyl ethyl ketone, and bitrex may also be included depending on regional regulations and intended use[1][2][3][10]. These additives make the solution toxic and unpalatable to prevent recreational consumption. Methylated spirit is highly flammable and volatile; it burns with a pale blue flame and evaporates quickly[4]. It acts as an effective solvent for cleaning hard surfaces (glass, metal), dissolving stains (glue, wax), sterilizing medical equipment due to its antibacterial properties[3][4], serving as fuel for burners or camping stoves[1][2], preserving laboratory specimens or cosmetics[4], and even acting as an insecticide. The mechanism of action in disinfection relies on protein denaturation in microorganisms via ethanol’s dehydrating effect.

Other names
denatured alcoholmethomethsdenatured rectified spiritindustrial methylated spiritsspecially methylated spirits
02

Targets

Bacterial Cell Membrane Proteins

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