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methylcellulose
- Development stage
- Phase 4
- Lead developer
- GSK
- Modality
- Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Small Molecules, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems
- Administration
- Oral, Ophthalmic, Topical
01
Overview
Methylcellulose is a semi-synthetic, hydrophilic derivative of cellulose used primarily as a bulk-forming laxative and an ophthalmic lubricant. When ingested, it absorbs water in the intestinal tract to increase stool bulk and moisture, thereby stimulating peristalsis and treating constipation. In ophthalmology, it is used in eye drops to relieve dry eye symptoms and as a viscoelastic agent during certain ocular procedures. Beyond its therapeutic uses, methylcellulose is widely employed as a thickening agent and emulsifier in the food and cosmetic industries, and as a vehicle for drug administration in preclinical research. In experimental ophthalmology, intraocular injection of methylcellulose is a standard method for inducing chronic ocular hypertension in animal models to study glaucoma.
- Brand names
- CitrucelMurocelMethocelGoniosol
- Other names
- Methyl celluloseCellulose methyl etherMC
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