Drug intelligence / Profile preview

methylcobalamin + alpha lipoic acid + pyridoxine + folic acid

Development stage
Unknown
Lead developer
Jenburkt Pharmaceuticals
Modality
Small Molecules
Administration
Oral
01

Overview

Nervijen is a multi-ingredient pharmaceutical product developed and marketed by Jenburkt Pharmaceuticals, primarily indicated for the management of peripheral neuropathy, including diabetic neuropathy. The formulation typically consists of **methylcobalamin** (an active form of Vitamin B12), **alpha lipoic acid** (thioctic acid), **pyridoxine** (Vitamin B6), and **folic acid**. Methylcobalamin acts as a cofactor for methionine synthase, which is essential for the synthesis of myelin and the regeneration of damaged neurons. Alpha lipoic acid serves as a potent antioxidant and a mitochondrial cofactor that helps reduce oxidative stress and improve nerve conduction velocity. Pyridoxine and folic acid support essential metabolic pathways and DNA repair mechanisms necessary for maintaining neuronal health. While primarily available as an oral capsule, the Nervijen brand also includes injectable formulations and variants with additional ingredients like benfotiamine.

Brand names
NervijenNervijen-Jenburkt
Other names
Nervijen Capsule
02

Targets

MTR (Methionine synthase)DDC (Aromatic L-amino acid decarboxylase)PDH (Pyruvate dehydrogenase complex)DHFR (Dihydrofolate reductase)

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