Drug intelligence / Profile preview

Methylplus

Development stage
Unknown
Lead developer
Biotics Research
Modality
Small Molecules
Administration
Oral
01

Overview

Methylplus is a dietary supplement formulated to support the body's methylation processes, which are essential for DNA synthesis, neurotransmitter production, and the detoxification of homocysteine. The formulation typically contains biologically active, pre-methylated forms of essential B-vitamins, including methylcobalamin (Vitamin B12), 5-methyltetrahydrofolate (5-MTHF), and pyridoxal-5-phosphate (Vitamin B6), alongside methyl donors such as trimethylglycine (betaine). By providing these specific vitamers, Methylplus bypasses the metabolic steps required to convert synthetic vitamins into their active forms, which is particularly relevant for individuals with genetic polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) enzyme. Its primary application is the management of healthy homocysteine levels and the support of cardiovascular and neurological health through the optimization of the methionine cycle.

Brand names
MethylplusMethyl Plus
Other names
Methylated B-complex supplement
02

Targets

MTR (Methionine synthase)

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