Drug intelligence / Profile preview

metronidazole

Development stage
Approved
Lead developer
Sanofi
Modality
Small Molecules
Administration
Oral, Intravenous, Topical, Vaginal, Rectal
01

Overview

Metronidazole is a nitroimidazole-class small molecule antibiotic and antiprotozoal agent. It is used to treat a variety of infections caused by anaerobic bacteria and certain protozoa, including trichomoniasis, amebiasis, giardiasis, bacterial vaginosis, pelvic inflammatory disease, pseudomembranous colitis, aspiration pneumonia, intra-abdominal infections, lung abscesses, periodontal disease, oral infections and rosacea. Metronidazole works by diffusing into the cytoplasm of susceptible organisms where it is reduced to active metabolites that disrupt DNA helical structure and cause strand breakage leading to cell death. It does not work against viral infections or aerobic bacteria[1][2][3][4][5][6][7][8].

Brand names
FlagylMetrogylLikmezRozexMetroGel
Other names
甲硝唑2-methyl-5-nitroimidazole ethanol灭滴灵 (Chinese)甲硝哒唑 (Chinese)甲硝基羟乙唑 (Chinese)甲硝达唑分离物 (Chinese)
02

Targets

Neuraminidase

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