metronidazole + piperacillin + tazobactam

This is a combination antibiotic therapy consisting of metronidazole (an antibiotic effective against anaerobic bacteria) and piperacillin/tazobactam (a combination of the broad-spectrum penicillin antibiotic piperacillin with the beta-lactamase inhibitor tazobactam). The combination provides coverage against a wide range of bacteria, including aerobic gram-positive, gram-negative, and anaerobic organisms. It's primarily used for treating complicated intra-abdominal infections, though clinical evidence suggests that using piperacillin/tazobactam plus metronidazole (double anaerobic coverage) may be associated with worse outcomes than piperacillin/tazobactam alone in some cases[4].