Drug intelligence / Profile preview

metronidazole + miconazole nitrate + lidocaine

Development stage
Unknown
Lead developer
Vefa İlaç
Modality
Small Molecules
Administration
Vaginal
01

Overview

Gynocain XL is a combination pharmaceutical product developed by Vefa İlaç for the treatment of mixed vaginal infections. It contains three active ingredients: metronidazole, an antibacterial and antiprotozoal agent; miconazole nitrate, a broad-spectrum antifungal; and lidocaine, a local anesthetic. Metronidazole is effective against anaerobic bacteria and *Trichomonas vaginalis*, while miconazole nitrate targets various fungi, including *Candida* species. Lidocaine is included to provide symptomatic relief from itching and irritation associated with vaginal infections. The XL designation typically refers to a high-dose formulation intended for a shorter treatment course. It is administered as a vaginal suppository (ovule).

Brand names
Gynocain XL
Other names
Gynocain XL Ovül
02

Targets

CYP51A1 (Sterol 14α-demethylase)NeuraminidaseNaV (Voltage-gated sodium channels)

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