Drug intelligence / Profile preview

Mexon

Development stage
Unknown
Lead developer
Sampharindo
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Mexon is an oral formulation of methylprednisolone, a synthetic glucocorticoid developed and marketed by the Indonesian pharmaceutical company Sampharindo. As a potent anti-inflammatory and immunosuppressive agent, it functions as an agonist of the glucocorticoid receptor (NR3C1). Upon binding to the receptor in the cytoplasm, the drug-receptor complex translocates to the nucleus, where it binds to glucocorticoid response elements (GREs) to modulate gene expression. This results in the downregulation of pro-inflammatory cytokines and the upregulation of anti-inflammatory mediators. Mexon is primarily indicated for the management of various inflammatory and autoimmune conditions, as well as acute allergic reactions.

Brand names
Mexon
Other names
methylprednisolone
02

Targets

GR (Glucocorticoid receptor)

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