Drug intelligence / Profile preview

MF268

Development stage
Unknown
Lead developer
Mediolanum
Modality
Small Molecules
Administration
Oral
01

Overview

MF268 is a small molecule cholinesterase inhibitor of the carbamate type that acts as a pseudo-reversible inhibitor. It interacts with both the catalytic and regulatory anionic sites of cholinesterase enzymes. Preclinical studies have shown that it increases extracellular acetylcholine levels in the cortex and has memory-enhancing activity in animal models. The compound belongs to the class of morpholines and was developed for potential use in Alzheimer's disease[1][2][3][4][5].

Other names
MF-268MF268MF 268MF 268 bitartrateMF268 bitartrateMF-268 bitartrate
02

Targets

ButyrylcholinesteraseAcetylcholinesterase

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