Drug intelligence / Profile preview

MG56-VII

Development stage
Unknown
Lead developer
Inmunotek
Modality
Sublingual Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Subcutaneous Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics
Administration
Sublingual
01

Overview

**MG56-VII** is the sublingual 3,000 mTU/mL treatment arm of Inmunotek's MG56 allergen-specific immunotherapy program. It consists of polymerized grass-pollen allergoids from *Dactylis glomerata* and *Phleum pratense* conjugated to mannan and was evaluated for grass pollen-induced allergic rhinitis and allergic rhinoconjunctivitis. In the Phase 2 MG56-SIT-012 dose-finding study, participants received a daily 0.2 mL sublingual dose for four months while receiving subcutaneous placebo in the double-dummy design. ([frontiersin.org](https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1431351/full))

02

Targets

Grass pollen allergen

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