Drug intelligence / Profile preview

MGT-006

Development stage
Phase 2
Lead developer
Metagen Therapeutics
Modality
Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

MGT-006 is an investigational oral microbiome therapy developed by Metagen Therapeutics for the treatment of moderately active ulcerative colitis. As a live biotherapeutic product, it consists of a defined or donor-derived microbial consortium encapsulated for oral delivery, aimed at restoring intestinal dysbiosis and modulating the mucosal immune response. The drug is currently undergoing Phase 1b/2a clinical evaluation in Japan and the United States, focusing on safety, tolerability, and the successful engraftment of therapeutic bacteria within the patient's gut microbiome.

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