Drug intelligence / Profile preview

MH-06

Development stage: Preclinical
Lead developer: Affiliated Suzhou Hospital of Nanjing Medical University
Modality: PROTACs (E3 ligase recruitment) → Targeted Protein Degraders (TPDs) → Small Molecules, Bivalent/Multivalent Binders → Multivalent & Scaffold-Based Small Molecules → Small Molecules

Overview

MH-06: sourced facts only. name: "Among these candidates, MH-06 was found to specifically target and effectively degrade ALOX12 protein." [PMID:42430827]; target: "Among these candidates, MH-06 was found to specifically target and effectively degrade ALOX12 protein." [PMID:42430827]; developer: "Department of Gastroenterology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Suzhou 215001, PR China." [PMID:42430827]; modality: "We further synthesized eight novel PROTAC molecules using linker-free PROTAC technology." [PMID:42430827]; stage: "In the cerulein-induced AP mouse model, MH-06 exerted remarkable therapeutic and preventive effects." [PMID:42430827]

Targets

ALOX12 (Arachidonate 12-lipoxygenase, 12S type)

Beyond the preview

Go deeper on MH-06.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on MH-06.