Drug intelligence / Profile preview

MHCR-1

Development stage
Preclinical
Lead developer
Odacova Health
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

MHCR-1 is a proprietary, botanical-derived bioactive ingredient developed by Odacova Health as a calorie restriction mimetic (CRM) for companion animals. Grounded in calorie-restriction-mimetic research and metabolic signaling, MHCR-1 is designed to translate the health and longevity benefits of calorie restriction into a practical healthy-aging platform for dogs without requiring reduced caloric intake. In a nine-year longitudinal canine research program, MHCR-1 demonstrated the ability to shift age-associated gene-expression patterns toward younger profiles, improve age-related fasting glucose trajectories, and preserve cumulative muscle power over time.

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