Drug intelligence / Profile preview

MI-10-022

Development stage
Unknown
Lead developer
Mithridion
Modality
Small Molecules
01

Overview

**MI-10-022** is a small molecule dual agonist targeting muscarinic acetylcholine receptors M1 and M4. These receptors are implicated in cognitive function and psychiatric disorders, with M1 activation enhancing memory and attention, and M4 modulation influencing dopamine signaling relevant to schizophrenia. Initially developed by Mithridion, Inc., a company focused on neurological therapies, the compound aimed to address unmet needs in cognitive impairment associated with neuropsychiatric conditions like Alzheimer's disease and schizophrenia through selective cholinergic potentiation.

02

Targets

CHRM4 (M4)M1 (Muscarinic acetylcholine receptor M1)

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