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mic-PtC5Mn
- Development stage
- Preclinical
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Stealth (PEGylated) Liposomes → Liposomes → Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
- Administration
- Intravenous
01
Overview
mic-PtC5Mn is a **PEGylated micelle formulation** containing the manganese-based prodrug PtC5Mn, designed for enhanced anticancer activity. The **mechanism of action** relies on improved delivery and release of the cytotoxic PtC5Mn compound within tumor tissue, resulting in potent antitumoral effects. This formulation demonstrates significantly suppressed tumor growth in vivo compared to PtC5Mn alone, highlighting the advantage of PEGylated micelle-based delivery for improving therapeutic outcomes. mic-PtC5Mn is an experimental agent under investigation for cancer therapy, primarily developed for anticancer indications[6][7].
- Brand names
- mic-PtC5Mnmic-PtC-5Mnmic-PtC 5Mn
- Other names
- mic-PtC5Mnmic-PtC-5Mnmic-PtC 5Mn
02
Targets
DNA
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