Drug intelligence / Profile preview

micellar glutathione

Development stage
Preclinical
Lead developer
Natural Factors
Modality
Small Molecules, Nanoparticles → Drug Delivery Systems
Administration
Oral
01

Overview

**Micellar glutathione** is a formulation of the antioxidant glutathione encapsulated in micelles to enhance absorption and bioavailability, particularly when delivered orally. Glutathione is a tripeptide composed of glutamic acid, cysteine, and glycine, and plays a crucial role in reducing oxidative stress, supporting tissue repair, detoxification, and modulating immune function[1][2][3][4][7][8]. The micellar formulation aims to improve stability and uptake of glutathione compared to standard oral glutathione supplements, as micelles can enhance the solubility and circulation time of their contents[9]. Primary indications include support for liver health, immune system function, management of oxidative stress, and potential adjunctive use in conditions such as fatty liver disease, neurodegenerative disorders, and as part of anti-aging regimens[1][2][4][8]. The specific mechanism of action is through direct neutralization of free radicals, maintenance of redox equilibrium, and facilitation of detoxification pathways[1][7].

Brand names
micellar glutathione
Other names
micellar glutathione
02

Targets

GST (Glutathione S-transferase alpha 3)GSH (Glutathione)

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