Micolette

Micolette is a rectal micro-enema developed by AFT Pharmaceuticals and Hyloris Pharmaceuticals for the treatment of constipation and for bowel cleansing prior to rectal examinations. It is a combination product containing sodium citrate, sodium lauryl sulfoacetate, and sorbitol. The mechanism of action involves osmotic and surfactant properties: sodium citrate and sorbitol act as osmotic laxatives by drawing water into the lower intestine to soften the stool, while sodium lauryl sulfoacetate serves as a wetting agent that reduces surface tension, allowing the liquid to penetrate the fecal mass. This localized action typically results in a bowel movement within 5 to 15 minutes. Micolette is positioned as a generic alternative to the established micro-enema product Microlax.

Brand names

Micolette

Other names

Micolette Micro-enema