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Micro V Probiotics (Sun Yat-sen University)
- Development stage
- Unknown
- Lead developer
- Sun Yat-sen University
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
Micro V Probiotics is a probiotic formulation being evaluated by Sun Yat-sen University for the treatment of primary biliary cholangitis (PBC). It is specifically targeted at patients who have shown a poor response to standard ursodeoxycholic acid (UDCA) monotherapy. The therapy aims to modulate the gut-liver axis by addressing intestinal flora dysbiosis, which is implicated in the pathogenesis of PBC. By altering the fecal microbial composition and metabolomics—including bile acids and short-chain fatty acids—the probiotic is intended to improve biochemical and immunological indicators of liver health and slow disease progression.
- Brand names
- Micro V Probiotics
- Other names
- Micro VProbiotic
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