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microbial extract
- Development stage
- Unknown
- Lead developer
- Uute Scientific
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Topical
01
Overview
Microbial extract is a topical microbial therapy derived from composted agricultural stack, gardening soils, deciduous leaf litter, peat, and Sphagnum moss. It is being investigated for its potential to treat atopic dermatitis by enhancing immune tolerance and mitigating eczema symptoms. The extract works by down-regulating pro-inflammatory cytokines such as IL-1β, IL-22, and IL-33, and the antimicrobial peptide human β-defensin 2.
02
Targets
IL33 (IL-33)DEFB4A (Human β-defensin-2)IL22 (Interleukin 22)IL1B (Interleukin-1 beta)
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