microporous biphasic calcium phosphate

Microporous biphasic calcium phosphate (MBCP) is a synthetic, osteoconductive bone substitute biomaterial composed of a stable phase of hydroxyapatite (HA) and a soluble phase of β-tricalcium phosphate (β-TCP). The material is engineered with a specific architecture of interconnected macropores and micropores, which facilitates the infiltration of bone-forming cells and the exchange of biological fluids. As the β-TCP component gradually resorbs, it releases calcium and phosphate ions into the local environment, promoting the mineralization and formation of new bone tissue. MBCP is primarily utilized as a scaffold in orthopedic and dental surgeries, including jaw bone reconstruction and alveolar ridge augmentation, often in combination with cellular therapies like mesenchymal stem cells to enhance regenerative outcomes.

Other names

biphasic calcium phosphateHA/TCPhydroxyapatite/beta-tricalcium phosphate