Drug intelligence / Profile preview

microRNA-223 mimic

Development stage
Preclinical
Modality
MicroRNA (miRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
01

Overview

microRNA-223 mimic is a **synthetic oligonucleotide RNA therapy** designed to restore or increase intracellular levels of the endogenous microRNA miR-223. Rather than being a uniquely identified branded or code-named drug, this term generally refers to research-use miR-223 replacement constructs used across preclinical studies to modulate gene-expression networks controlled by miR-223. Its intended pharmacology is sequence-based post-transcriptional repression of miR-223 target mRNAs through the RNA-induced silencing complex, with reported investigation in cancer and inflammatory biology, including studies of cholesterol homeostasis and tamoxifen resistance in breast cancer. Based on the provided evidence, this appears to be a non-specific therapeutic concept rather than a single clearly defined clinical asset from a named developer.

Other names
miRNA-223 mimicmiRNA223 mimicmiRNA 223 mimicmiR-223 mimicmiR223 mimicmiR 223 mimicmicroRNA-223 mimicmicroRNA223 mimicmicroRNA 223 mimic
02

Targets

FBXW7FOXO1 (Forkhead box protein O1)PDE4D (Phosphodiesterase 4D)STIM1 (Stromal interaction molecule 1)IGF-1R (Insulin-like growth factor 1 receptor)TOX (Thymocyte selection-associated high mobility group box protein)

Beyond the preview

Go deeper on microRNA-223 mimic.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on microRNA-223 mimic.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call