Drug intelligence / Profile preview

Micrurus frontalis venom

Development stage
Unknown
Lead developer
Fundação Ezequiel Dias
01

Overview

Micrurus frontalis venom is the crude venom of the South American coral snake *Micrurus frontalis*. It is a complex biological mixture composed primarily of neurotoxic three-finger toxins (frontoxins) and phospholipases A2 (PLA2). The venom's primary toxic mechanism is the blockade of nicotinic acetylcholine receptors at the neuromuscular junction, leading to neuromuscular blockade and muscle paralysis. In Brazil, this venom is utilized as an immunogen to hyperimmunize horses for the production of bivalent coral snake antivenom (antielapidic serum) by the Instituto Butantan and Fundação Ezequiel Dias (FUNED). It is not used as a therapeutic agent for any disease.

Other names
Micrurus frontalis crude venom
02

Targets

Nicotinic Acetylcholine Receptor

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