Drug intelligence / Profile preview

mineral oil + petrolatum

Development stage
Unknown
Lead developer
Alcon
Modality
Small Molecules
Administration
Topical, Ophthalmic
01

Overview

Mineral oil + petrolatum is an over-the-counter (OTC) combination product used as an emollient and lubricant. It is available in ophthalmic formulations (eye ointments) for treating dry eyes and topical formulations (creams and ointments) for dry, itchy, or irritated skin. The active ingredients are petroleum-derived hydrocarbons that work by forming an occlusive layer on the skin or ocular surface, which traps moisture and provides a physical barrier against environmental irritants like wind or cold. Because it functions through physical rather than pharmacological means, it has no specific biological target. It is widely available under various brand names and is generally well-tolerated.

Brand names
Systane Nighttime Lubricant Eye OintmentRefresh P.M.Lacri-LubeDuolube
Other names
liquid paraffin + white soft paraffinwhite petrolatum + mineral oil

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