Drug intelligence / Profile preview

Mingmu Dihuang Pills

Development stage
Unknown
Lead developer
Lanzhou Foci
Modality
Small Molecules
Administration
Oral
01

Overview

Mingmu Dihuang Pills (Ming Mu Di Huang Wan) is a traditional Chinese medicine (TCM) formulation developed and marketed by Lanzhou Foci Pharmaceutical. It is a concentrated pill for oral administration, primarily indicated for nourishing the kidney and liver and improving vision. According to TCM principles, it is used to treat liver-kidney yin deficiency, which manifests as dry eyes, photophobia, blurred vision, and tearing when exposed to wind. The formulation is a complex herbal mixture containing twelve ingredients, including prepared rehmannia root, wolfberry, chrysanthemum, and abalone shell. It is listed as a National Essential Drug in China and is also marketed internationally as a dietary herbal supplement.

Brand names
Lanzhou Foci
Other names
Ming Mu Di Huang Wan明目地黄丸
02

Targets

AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)SRC (Proto-oncogene tyrosine-protein kinase Src)VEGFA (Vascular endothelial growth factor A)AMPK (Adenosine monophosphate–activated protein kinase)KEAP1 (Kelch-like ECH-associated protein 1)SQSTM1 (Sequestosome-1)

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