Drug intelligence / Profile preview

miR-143-3p inhibitor

Development stage
Preclinical
Modality
Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Single-strand DNA → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Modified DNA Oligonucleotides → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics
01

Overview

miR-143-3p inhibitor is a chemically modified antisense oligonucleotide designed to specifically bind and inhibit the mature microRNA miR-143-3p. In preclinical research, miR-143-3p inhibitors are utilized to investigate the role of miR-143-3p in various pathological conditions, including benign prostatic hyperplasia (BPH), preeclampsia, and various cancers. By blocking miR-143-3p, these inhibitors prevent the downregulation of its target genes, thereby modulating cellular functions such as contractility, proliferation, and apoptosis.

Other names
anti-miR-143-3panti-miR143-3panti-miR 143-3pmicroRNA-143-3p inhibitormicroRNA143-3p inhibitormicroRNA 143-3p inhibitormiR-143-3p antagomirmiR143-3p antagomirmiR 143-3p antagomir
02

Targets

miR-143-3p (MicroRNA 143-3p)

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