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miR-16 antagomiR

Development stage: Unknown
Modality: MicroRNA (miRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Administration: Intramuscular, Intravenous, Local Injection (e.g., Into The Brain)

Overview

miR-16 antagomiR is a chemically modified oligonucleotide designed to inhibit the function of microRNA-16 (miR-16). It acts by binding to miR-16, preventing it from regulating gene expression. This mechanism is crucial for studying miRNA function and has potential therapeutic applications. The drug is typically administered via intramuscular or intravenous routes for systemic delivery but requires local injection, such as into the brain, to bypass certain barriers like the blood-brain barrier[1][2].

Other names: antagomir against miR-16

Targets

miR-16 (MicroRNA-16)

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