miR-182-5p inhibitor

miR-182-5p inhibitor refers to a class of molecular agents, typically antisense oligonucleotides (antagomirs), designed to specifically bind and sequester microRNA-182-5p (miR-182-5p). miR-182-5p is an oncogenic microRNA that is frequently overexpressed in various malignancies, including bladder cancer, where it promotes tumor progression by silencing tumor suppressor genes such as Smad4 and RECK. By inhibiting miR-182-5p, these inhibitors facilitate the restoration of target gene expression, thereby suppressing cell proliferation, migration, and invasion, and potentially inhibiting the Wnt/beta-catenin signaling pathway. While primarily used as a research tool to study miRNA function, miR-182-5p inhibitors represent a potential therapeutic strategy for cancers characterized by miR-182-5p dysregulation.

Other names

antagomir-182-5pantagomir182-5pantagomir 182-5panti-miR-182-5panti-miR182-5panti-miR 182-5pmiRNA-182-5p inhibitormiRNA182-5p inhibitormiRNA 182-5p inhibitor