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miR-665 mimic
- Development stage
- Unknown
- Modality
- MicroRNA (miRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
- Administration
- Intravenous, Intraperitoneal, Intradermal
01
Overview
miR-665 mimic is an experimental research compound consisting of a small, chemically synthesized double-stranded RNA molecule designed to mimic the activity of the endogenous microRNA miR-665 (hsa-miR-665). It is used in preclinical and academic research settings to study the functional role of miR-665 by upregulating miRNA activity in cell and animal models. The compound has no single developing company, brand name, or approved clinical indication, and is synthesized by various reagent suppliers (such as MedChemExpress and GenePharma) for experimental use. Studies have investigated the miR-665 mimic in several disease contexts, including sevoflurane anesthesia-induced cognitive dysfunction, myocardial ischemia-reperfusion injury, lung squamous cell carcinoma, breast cancer metastasis, and cardiac hypertrophy.
- Other names
- hsa-miR-665 mimichsa-miR665 mimichsa-miR 665 mimicmicroRNA-665 mimicmicroRNA665 mimicmicroRNA 665 mimicrno-miR-665 mimicrno-miR665 mimicrno-miR 665 mimic
02
Targets
LASP1 (LIM and SH3 domain protein 1)NR4A3 (Nuclear receptor subfamily 4 group A member 3)CD34 (Hematopoietic progenitor cell antigen CD34)E3 ligase (E3 ubiquitin ligases)MYC (MYC proto-oncogene protein)CNR2 (Cannabinoid receptor type 2)
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