Drug intelligence / Profile preview

miR-96-5p agomir

Development stage
Unknown
Modality
Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, MicroRNA (miRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics
Administration
Intrathecal, Intravitreal, Parenteral
01

Overview

miR-96-5p agomir is a chemically modified, double-stranded microRNA (miRNA) mimic designed to overexpress miR-96-5p in vitro and in vivo. It is primarily utilized as a research tool to investigate the physiological and pathological roles of miR-96-5p. In preclinical models, miR-96-5p agomir has been studied for its potential therapeutic effects in polycystic ovary syndrome (PCOS), where it targets forkhead box O1 (FOXO1) to regulate estrogen synthesis and granulosa cell proliferation. It has also been investigated in models of acute ischemic stroke, where it downregulates caspase-1 to inhibit pyroptosis and reduce brain damage, as well as in models of choroidal neovascularization (CNV) and arsenic-induced skin cancer.

Other names
hsa-miR-96-5p agomirhsa-miR96-5p agomirhsa-miR 96-5p agomirmiR-96-5p agomirmiR96-5p agomirmiR 96-5p agomirmmu-miR-96-5p agomirmmu-miR96-5p agomirmmu-miR 96-5p agomirrno-miR-96-5p agomirrno-miR96-5p agomirrno-miR 96-5p agomir
02

Targets

CASP1 (Caspase-1)CASP9 (Caspase-9)FOXO1 (Forkhead box protein O1)FOXO3 (Forkhead box protein O3)GPC1 (Glypican-1)SMAD7 (Mothers against decapentaplegic homolog 7)TP73 (Tumor protein p73)

Beyond the preview

Go deeper on miR-96-5p agomir.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on miR-96-5p agomir.

Gosset Free

Get started with Gosset.

Enter your corporate email.

Work email preferred.

Book a call