miR-Y LNA inhibitor

miR-Y LNA inhibitor (also known as miR-375-3p LNA inhibitor) is a locked nucleic acid (LNA)-based antisense oligonucleotide designed to inhibit microRNA-375-3p (miR-375-3p). Developed by researchers at the University Hospital Halle (Saale), this inhibitor is used to study the role of miR-375-3p in cellular senescence, endothelial dysfunction, and vascular aging. In vitro and in vivo preclinical studies have shown that inhibition of miR-375-3p enhances the angiogenic and regenerative capacity of both non-senescent and replicative senescent human coronary artery endothelial cells (HCAEC), although its effects on inflammatory signaling and cell survival are complex and require further investigation.

Other names

anti-miR-375-3p LNA inhibitoranti-miR375-3p LNA inhibitoranti-miR 375-3p LNA inhibitormiR-375-3p LNA inhibitormiR375-3p LNA inhibitormiR 375-3p LNA inhibitormicroRNA-375-3p LNA inhibitormicroRNA375-3p LNA inhibitormicroRNA 375-3p LNA inhibitor