Drug intelligence / Profile preview

mirena

Development stage
Approved
Lead developer
Bayer
Modality
Small Molecules
Administration
Intrauterine (iud)
01

Overview

Mirena is a hormone-releasing intrauterine device (IUD) that contains the active ingredient levonorgestrel, a synthetic progestin. It is a T-shaped plastic device inserted into the uterus by a healthcare provider. Mirena provides long-term contraception for up to 8 years and is also approved for the treatment of heavy menstrual bleeding (menorrhagia) in women who choose an IUD for contraception, with efficacy for up to 5 years[1][2][4][5][7]. The mechanism of action involves local release of levonorgestrel in the uterine cavity, which thickens cervical mucus to inhibit sperm passage, alters the endometrial lining to prevent implantation, and may partially suppress ovulation in some users[3][4][6]. Only small amounts of hormone reach systemic circulation. Mirena does not contain estrogen and should not be used as emergency contraception.

Brand names
Mirena
Other names
levonorgestrel-releasing intrauterine systemlevonorgestrel IUD
02

Targets

PR (Progesterone receptor)

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