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miroliver ELAP
- Development stage
- Unknown
- Lead developer
- United Therapeutics
- Modality
- Tissue Cells → Other Cell Types → Cell Therapies, Stem Cell Therapies → Cell Therapies
- Administration
- Extracorporeal
01
Overview
miroliver ELAP is a first-of-its-kind bioengineered liver system designed to provide external metabolic and synthetic support for patients suffering from acute liver failure (ALF). Developed by Miromatrix Medical (now a subsidiary of United Therapeutics), the technology utilizes a decellularized porcine liver scaffold that is recellularized with functional human hepatocytes. This bioengineered organ is housed within an extracorporeal blood circuit, functioning similarly to a dialysis system. As the patient's blood circulates through the miroliver ELAP, the human cells within the scaffold perform essential liver functions, including detoxification and protein synthesis, serving as a bridge to either spontaneous liver recovery or a successful liver transplant.
- Brand names
- miroliverELAP
- Other names
- Extracorporeal Liver Assist ProductBioengineered LiverMiromatrix Bioengineered Liver
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