Drug intelligence / Profile preview

Misotac

Development stage
Phase 3
Lead developer
Pfizer
Modality
Small Molecules
Administration
Oral, Sublingual, Vaginal, Rectal
01

Overview

Misotac is a pharmaceutical product containing misoprostol, a synthetic analogue of prostaglandin E1 (PGE1). Produced by Sigma Pharmaceutical Industries in Egypt, it is typically formulated as 200 microgram tablets for oral, sublingual, vaginal, or rectal administration. The drug is extensively utilized in obstetrics and gynecology for its potent uterotonic and cervical-ripening properties. Its primary mechanism of action involves acting as an agonist at prostaglandin receptors in the uterine myometrium, leading to increased strength and frequency of contractions, and in the cervix, where it promotes collagen degradation and softening. Clinically, Misotac is employed for medical abortion, induction of labor, the prevention and treatment of postpartum hemorrhage (particularly during cesarean sections), and cervical priming prior to diagnostic or surgical procedures. It is also being investigated for reducing blood loss in surgeries such as myomectomies and treating abnormal uterine bleeding associated with isthmocele. Misotac's stability at room temperature and ease of administration make it a critical therapeutic option in various clinical settings.

Brand names
Misotac
Other names
misoprostol
02

Targets

PTGER3 (Prostaglandin E2 receptor EP3 subtype)PTGER4 (Prostaglandin E2 receptor EP4 subtype)PTGER2 (Prostaglandin E2 receptor EP2)

Beyond the preview

Go deeper on Misotac.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Misotac.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call