Drug intelligence / Profile preview

Mitomycin C RTGel

Development stage: Phase 3
Lead developer: UroGen Pharma
Modality: Small Molecules, Hydrogel Systems → Drug Delivery Systems
Administration: Intrarenal, Intraureteral

Overview

UGN-104 is a next-generation hydrogel-based sustained-release formulation of mitomycin C developed by UroGen Pharma for the treatment of low-grade upper tract urothelial cancer (LG-UTUC). It utilizes UroGen’s proprietary RTGel technology to enable prolonged local exposure of the urinary tract to mitomycin following instillation via ureteral catheter or nephrostomy tube. The drug acts as a **DNA synthesis inhibitor** and offers a non-surgical therapeutic option for patients with LG-UTUC. UGN-104 is designed to improve upon previous formulations by streamlining manufacturing and reconstitution processes while providing extended intellectual property protection[1][4][7].

Other names: mitomycinmitomycin CMitomycin 0.18% gelMitomycin 0.4% gelMMC gelMITOGEL

Targets

DNA

Beyond the preview

Go deeper on Mitomycin C RTGel.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on Mitomycin C RTGel.