Drug intelligence / Profile preview

MK-0719

Development stage: Phase 2
Lead developer: Merck
Modality: Small Molecules
Administration: Oral

Overview

MK-0719 is a small molecule drug that was initially developed by Merck & Co. for the treatment of pain, specifically targeting postoperative dental pain and toothache. The drug reached Phase 2 clinical trials, where it was evaluated for safety, tolerability, and efficacy in preventing postoperative dental pain compared to placebo and ibuprofen in male patients undergoing third molar extraction. Its development has since been discontinued, and no further clinical advancement or approval has been reported. The precise molecular target and mechanism of action have not been publicly disclosed.

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