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MK-1966
- Development stage
- Discontinued
- Lead developer
- Merck
- Modality
- Antibody-Based Therapeutics
- Administration
- Intravenous
01
Overview
MK-1966 is an investigational anti-interleukin-10 (anti-IL-10) immunomodulator developed by Merck. It is a monoclonal antibody designed to neutralize the activity of the anti-inflammatory cytokine human interleukin-10 (IL-10), thereby reducing immune suppression in the tumor microenvironment and potentially enhancing antitumor immune responses. The drug was primarily investigated for oncology indications, aiming to modulate immune responses against cancer cells. Clinical development reached Phase 1, but trials were terminated before completion[1][2][3][4][5].
- Other names
- IL-10 immunomodulator MK-1966IL10 immunomodulator MK-1966IL 10 immunomodulator MK-1966
02
Targets
IL10 (Interleukin-10)
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