Drug intelligence / Profile preview

MK-633

Development stage
Phase 2
Lead developer
Merck
Modality
Small Molecules
Administration
Oral
01

Overview

MK-633 is an oral agent that was under development by Merck for the treatment of Chronic Obstructive Pulmonary Disease (COPD). The drug was investigated as a potential therapy to address respiratory symptoms and disease progression in COPD, but there is no evidence it reached advanced clinical development or approval. Its precise mechanism of action has not been publicly disclosed.

Other names
setileuton
02

Targets

P2XR (P2X receptor family)P2X3 (P2X purinoceptor 3)ALOX5 (Arachidonate 5-lipoxygenase)

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