Drug intelligence / Profile preview

MKL001

Development stage
Preclinical
Lead developer
MiHKAL
Modality
Small Molecules
01

Overview

MKL001 is a preclinical-stage small molecule prodrug being developed by the Swiss pharmaceutical company MiHKAL GmbH for the treatment of Post-Traumatic Stress Disorder (PTSD). The drug is engineered to be enzymatically activated in human blood, employing a prodrug strategy similar to that of lisdexamfetamine (Vyvanse) to provide tunable release kinetics. This activation mechanism has been validated through in vitro digestion assays. While the specific active ingredient and its biological targets remain undisclosed, MKL001 represents one of the lead candidates in MiHKAL's pipeline focused on addressing the unmet needs of patients with PTSD.

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