Drug intelligence / Profile preview

MMJ-002

Development stage
Phase 3
Lead developer
MMJ International Holdings
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Drug Delivery Systems
Administration
Oral
01

Overview

MMJ-002 is a proprietary, cannabinoid-based investigational drug developed by MMJ International Holdings for the treatment of Huntington’s disease, specifically targeting chorea associated with the condition. The formulation contains highly purified cannabidiol (CBD) and tetrahydrocannabinol (THC), delivered as an oral gel capsule. Unlike recreational cannabis products, MMJ-002 is designed to provide therapeutic benefits without the psychoactive side effects typically associated with cannabis use. The drug has received Orphan Drug designation from the U.S. Food and Drug Administration (FDA), which supports its development for rare diseases like Huntington’s disease and provides incentives such as marketing exclusivity and tax credits for clinical trials. A Phase 2 clinical trial is planned to evaluate its efficacy in mitigating involuntary movements in Huntington’s patients[1][3][4][6][7].

02

Targets

CNR1 (Cannabinoid receptor 1)

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