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MMR vaccine-MCM Vaccines B.V.-diphtheria-tetanus-pertussis-poliomyelitis-Haemophilus influenzae type b infection-hepatitis B-meningococcal meningitis (serogroup C)

Development stage
Unknown
Lead developer
Merck
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

This entry refers to a pediatric vaccination regimen involving the concomitant administration of three distinct vaccine products: the hexavalent vaccine **Vaxelis** (developed by **MCM Vaccines B.V.**), a **Measles, Mumps, and Rubella (MMR) vaccine**, and a **Meningococcal serogroup C (MCC) conjugate vaccine**. Vaxelis (V419) provides active immunization against diphtheria, tetanus, pertussis, poliomyelitis, hepatitis B, and invasive disease caused by Haemophilus influenzae type b. The MMR vaccine protects against measles, mumps, and rubella, while the MCC vaccine targets Neisseria meningitidis serogroup C. This specific co-administration schedule has been evaluated in Phase III clinical trials to ensure the safety and immunogenicity of these vaccines when given during the same clinical visit to infants aged 2 to 12 months.

Brand names
VaxelisM-M-R IINeisVac-CMenjugate
Other names
Vaxelis + MMR + MenCDTaP5-HBV-IPV-Hib + MMR + MCC
02

Targets

FHA (Filamentous hemagglutinin)HBsAg (Hepatitis B surface antigen)Poliovirus capsid proteinsMV (Measles virus)Mumps virus antigenNeisseria meningitidis group C capsular polysaccharidePRN (Pertactin)FIM2/FIM3 (Fimbriae types 2 and 3)TT (Tetanus toxoid)Fimbrial antigen type 3Poliovirus type 1 capsid proteinWPV3 (Poliovirus type 3 capsid protein)

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