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MNC-026
- Development stage
- Preclinical
- Lead developer
- MoonBio
- Modality
- Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics
01
Overview
MNC-026 is a live biotherapeutic product (LBP) developed by MoonBio (Moons) for the treatment of solid tumors. As an immuno-oncology (IO) microbiome-based therapy, it consists of specific bacterial strains designed to modulate the gut microbiota to enhance anti-tumor immune responses. The drug is intended to function by altering the microbial environment in the gut to stimulate systemic immunity, potentially improving the efficacy of other cancer treatments or acting as a standalone therapy. MNC-026 is currently in the IND-enabling or early clinical stage of development.
- Other names
- MNC-026 (IO LBP)
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