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MNI-672
- Development stage
- Phase 1
- Lead developer
- Molecular NeuroImaging
- Modality
- Small Molecules, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
- Administration
- Intravenous
01
Overview
MNI-672 is an Iodine-123 labeled radiopharmaceutical developed by Molecular NeuroImaging (now part of Invicro) for the diagnostic imaging of cerebral beta-amyloid (Aβ) plaques using Single Photon Emission Computed Tomography (SPECT). As a small molecule tracer, MNI-672 binds specifically to Aβ deposits in the brain, which are a primary pathological hallmark of Alzheimer's disease. By enabling the visualization and quantification of amyloid burden, MNI-672 serves as a diagnostic tool to assist in the detection or exclusion of Alzheimer's pathology in patients with cognitive impairment. The use of SPECT imaging with MNI-672 offers a potentially more accessible and cost-effective alternative to PET-based amyloid imaging agents.
- Other names
- mni-672mni672mni 672123i-mni-672iodine-123 mni 672iodine123 mni 672iodine 123 mni 672
02
Targets
Amyloid-beta aggregate (N-terminal epitope)
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