Drug intelligence / Profile preview

Mobithron Advance

Development stage
Phase 1
Lead developer
Brego Life Sciences
Modality
Recombinant Proteins and Enzymes, Small Molecules
Administration
Oral
01

Overview

Mobithron Advance is a multi-ingredient nutraceutical supplement developed and marketed by Brego Life Sciences for the management of osteoarthritis, specifically targeting knee osteoarthritis. The formulation contains three primary active components: undenatured type II collagen (Collavant n2), hyaluronic acid (Mobilee), and a patented Boswellia serrata gum extract (Apresflex). Undenatured type II collagen works via an oral tolerance mechanism to modulate the immune response and preserve joint cartilage. Hyaluronic acid provides essential lubrication and cushioning within the synovial fluid to improve joint mobility. Boswellia serrata extract acts as a potent anti-inflammatory agent by inhibiting the 5-lipoxygenase (5-LOX) enzyme, thereby reducing the production of pro-inflammatory leukotrienes. Universiti Sains Malaysia is currently conducting a prospective clinical trial to evaluate the long-term safety, efficacy, and cartilage-preserving effects of Mobithron Advance in patients with Kellgren-Lawrence grade 1 to 3 knee osteoarthritis.

Brand names
Mobithron Advance
Other names
type 2 collagen-Universiti Sains Malaysia-osteoarthritistype2 collagen-Universiti Sains Malaysia-osteoarthritistype-2 collagen-Universiti Sains Malaysia-osteoarthritis
02

Targets

CD44 (CD44 antigen)ALOX12 (Arachidonate 12-lipoxygenase, 12S type)

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