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ModCAR-CD19 is a modular chimeric antigen receptor (CAR) cell therapy being developed by Hauul Bio for the treatment of CD19-positive hematological malignancies. The therapy utilizes a modular CAR design, which is intended to provide enhanced control over cell activity and targeting compared to traditional CAR-T therapies. It is currently in preclinical development for a range of blood cancers, including acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), diffuse large B-cell lymphoma (DLBCL), chronic myeloid leukemia (CML), chronic lymphocytic leukemia (CLL), and non-Hodgkin lymphoma (NHL).
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