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Drug intelligence / Profile preview
ModCAR CD19
- Development stage
- Preclinical
- Lead developer
- Hauul Bio
- Modality
- CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies
- Administration
- Intravenous
01
Overview
ModCAR CD19 is a non-viral modular chimeric antigen receptor (CAR) cell therapy being developed by Hauul Bio for the treatment of hematologic malignancies. Unlike conventional viral-vector-based CAR-T therapies, the ModCAR platform utilizes a non-viral approach where immune cells are engineered with a modular CAR system. This system employs a recombinant single-chain variable fragment (scFv) fusion protein to specifically recognize and bind B-lymphocyte antigen CD19 on malignant cells. By separating the antigen-recognition domain from the cell-activation machinery in a modular format, this technology aims to simplify the manufacturing process, enhance safety, and provide a highly customizable therapeutic option. The program is currently in the discovery and research stage.
- Other names
- ModCAR-CD19ModCAR-CD-19ModCAR-CD 19
02
Targets
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