Drug intelligence / Profile preview

ModCAR Mesothelin

Development stage
Preclinical
Lead developer
Hauul Bio
Modality
Cell Therapies
Administration
Intravenous
01

Overview

ModCAR Mesothelin is an investigational non-viral modular chimeric antigen receptor (CAR) cell therapy being developed by Hauul Bio for the treatment of solid cancers. Utilizing Hauul Bio's proprietary ModCAR platform, the therapy employs a modular single-chain variable fragment (scFv)-fusion protein designed to recognize and bind mesothelin-positive tumor cells. Unlike conventional viral-vector-based CAR therapies, this non-viral modular approach aims to simplify the manufacturing process, reduce production costs, and offer a highly customizable, off-the-shelf treatment option for patients with mesothelin-expressing solid tumors.

Other names
ModCAR-Mesothelin
02

Targets

Mesothelin

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